Tony Schmidt

is an electrophysiologist with expertise in optical neurostimulation and bioelectronic interfaces, focusing on light-responsive materials and optoelectronic strategies for neuromodulation. His research integrates high-resolution patch-clamp electrophysiology with advanced LED-based stimulation systems and organic semiconducting platforms to achieve precise spatio-temporal control of excitable cells. A central aim of his work is the development of light-activated approaches for cortical stimulation and retinal signal transduction recovery in degenerative conditions.

In addition, he applies photopharmacological tools in C. elegans and mammalian model systems to dissect TRP channel–dependent signalling pathways and their roles in neuronal function, plasticity, and repair. Within TRPC.at, his research encompasses redox-sensitive TRP channel modulation and photoregulation in both neuronal and cardiac contexts, combining electrophysiology, genetically encoded biosensors, and computational modelling to understand ROS-dependent gating and Ca²⁺ signalling dynamics.

Within TRPC.at, he collaborates with Schindl/ Tiapko (bioelectronic neuromodulation, TRPC electrophysiology and channel biophysics), Heijman (computational modelling of cardiac electrophysiology), Malli/Gottschalk (genetically encoded biosensors and super-resolution Ca²⁺ imaging), and Madreiter-Sokolowski (ROS homeostasis and cellular signalling complexes).

Links: Institutional Website

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